THE DEUBIQUITINASE USP47 STABILIZES MAPK BY COUNTERACTING THE FUNCTION OF THE N-END RULE LIGASE POE/UBR4 IN DROSOPHILA.

The Deubiquitinase USP47 Stabilizes MAPK by Counteracting the Function of the N-end Rule ligase POE/UBR4 in Drosophila.

RAS-induced MAPK signaling is a central driver of the cell proliferation apparatus.Disruption of this pathway is widely observed in cancer and other pathologies.Consequently, considerable effort has been devoted to understanding the mechanistic aspects of RAS-MAPK signal transmission and regulation.While much information has been garnered on the st

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The LOV protein of Xanthomonas citri subsp. citri plays a significant role in the counteraction of plant immune responses during citrus canker.

Pathogens interaction with a host plant starts a set of immune responses that result in complex changes in gene expression and plant physiology.Light is an important modulator of plant defense response and recent studies have evidenced the novel influence of this environmental stimulus in the virulence of several bacterial pathogens.Xanthomonas cit

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Well-being Therapy: Review of Studies Evaluating the Effectiveness and Prospects for the Development of a Positive Psychotherapeutic Strategy

Well-being therapy was developed in the 1990s on the basis of a model of psychological well-being describing the components of positive psychological functioning, and then revised within the framework of the strikketøy oppbevaring concept of euthymia, defending the idea of a balance of positive and negative psychological characteristics.Being a sh

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Adult-onset Kawasaki disease (mucocutaneous lymph node syndrome) and concurrent Coxsackievirus A4 infection: a case report

Yuki Ueda,1 Tsuneaki Kenzaka,1,2 Ayako Noda,1 Yu Yamamoto,1 Masami Matsumura1 1Division of General Internal Medicine, Jichi Medical University Hospital, Shimotsuke, 2Division of Community Medicine and Career Development, Kobe keychron m4 University Graduate School of Medicine, Japan Introduction: Kawasaki disease (KD) most commonly develops in infa

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